{"id":1123,"date":"2013-06-23T04:28:18","date_gmt":"2013-06-23T04:28:18","guid":{"rendered":"https:\/\/andreasphysioblog.com\/?p=1123"},"modified":"2021-04-01T20:50:36","modified_gmt":"2021-04-01T20:50:36","slug":"laendesmerter-antibiotika-modic-forandringer-fysioterapi-nobelpris-modtagelse","status":"publish","type":"post","link":"https:\/\/andreasphysioblog.com\/?p=1123","title":{"rendered":"L\u00e6ndesmerter Antibiotika Modic-forandringer"},"content":{"rendered":"<ul>\n<li><a href=\"https:\/\/www.facebook.com\/pages\/Andreasbjerregaardwordpresscom\/1460600300839186\">Andreasbjerregaard.wordpress.com<\/a><\/li>\n<li><a href=\"https:\/\/www.facebook.com\/pages\/S%C3%B8ernes-Fysioterapi\/1470212533260034\">S\u00f8ernesfysioterapi<\/a><\/li>\n<\/ul>\n<p><strong>L\u00e6nderyg problemer kan behandles med antibiotika<\/strong><\/p>\n<p>Ny forskning viser at en antibiotikakur kan reducere kroniske rygsmerter efter en diskusprolaps. Bag forskningsresultaterne er et hold af fysioterapeuter og eksperter fra Syddansk Universitet\u00a0med Hanne Albert i spidsen, som gennem de seneste +10 \u00e5r har studerede antibiotika til behandling af l\u00e6nderygsmerter. Forskningen har v\u00e6ret finansieres af seks danske fonde og Gigtforeningen.<\/p>\n<p>Forskernes hypotese var, at nogle af rygsmerterne kunne skyldtes bakterier efter en injektion eller efter fx tandb\u00f8rstning.<br \/>\nFors\u00f8gene viste, at en betydelig procentdel af patienter med kronisk \u2018lavere\u2019 estimerede rygsmerter kan blive hjulpet eller have gavn af en 100-dages kur med antibiotikabehandling.<\/p>\n<p><strong>Hvad<\/strong><\/p>\n<p>Deres forskningen byggede p\u00e5\u00a0hvordan bakterielle infektioner i diskusmaterialet, ved en diskusprolaps, kunne forudsage smertefulde bet\u00e6ndelse tilstande og sm\u00e5 frakturer i den omgivende ryghvirvler [Albert, Lambert et al. 2013].\u00a0Disse forandringer blev\u00a0klassificererede efter Modic systemet, der i slutningen af 1980\u2019erne blev udviklet af Michael Modic til at beskrive forandringer i de lumbale l\u00e6ndehvirvlerne gennem MR-scanninger. P\u00e5 MR-scanninger kan der ved kronisk smertepatienter observeres nogle hvide pletter som sidder overfor- og nedenunder den tidl. prolaps. Det er disse hvide pletter som havde interesseret forskerholdet.<\/p>\n<p>Modic forandringer er en betegnelse for mikrobrud i rygs\u00f8jlen, som skaber en slags knogle\u00f8dem, som kan v\u00e6re yderst smertefulde for patienten. Dette heler sig selv i l\u00f8bet af 10-12 \u00e5r. (fysioterapeuten, 06 \/juni 2013).\u00a0Modic-forandringer \u00a0synes derfor at v\u00e6re forbundet med l\u00e6ndesmerter og kunne udg\u00f8re en pre-anatomisk \u00e5rsag til smerten.<\/p>\n<p><strong>\u00a0\u00a0<a href=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-07-55.png\"><img decoding=\"async\" class=\"alignright wp-image-3879 \" src=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-07-55.png?w=145&amp;h=112\" sizes=\"(max-width: 145px) 100vw, 145px\" srcset=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-07-55.png?w=145&amp;h=112 145w, https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-07-55.png?w=290&amp;h=224 290w, https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-07-55.png?w=150&amp;h=115 150w\" alt=\"Sk\u00e6rmbillede 2014-07-10 kl. 00.07.55\" width=\"145\" height=\"112\" data-attachment-id=\"3879\" data-permalink=\"https:\/\/physioblogandreasbjerregaard.com\/2013\/06\/23\/laendesmerter-antibiotika-modic-forandringer-fysioterapi-nobelpris-modtagelse\/skaermbillede-2014-07-10-kl-00-07-55\/\" data-orig-file=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-07-55.png\" data-orig-size=\"1030,792\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;}\" data-image-title=\"Sk\u00e6rmbillede 2014-07-10 kl. 00.07.55\" data-image-description=\"\" data-medium-file=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-07-55.png?w=300\" data-large-file=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-07-55.png?w=825\" \/><\/a>Klassiferingsfaser kaldes:<\/strong><\/p>\n<ul>\n<li>Type 1, hvilket afspejler hypervaskularitet i hvirvlerne, sandsynligvis som et resultat af inflammation og \u00f8dem.<\/li>\n<li>Type 2 best\u00e5r af et gult fedtholdige udskiftninger af r\u00f8de knoglemarv i ryghvirvler.<\/li>\n<li><a href=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-08-05.png\"><img decoding=\"async\" class=\"alignright wp-image-3880 \" src=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-08-05.png?w=151&amp;h=116\" sizes=\"(max-width: 151px) 100vw, 151px\" srcset=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-08-05.png?w=151&amp;h=116 151w, https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-08-05.png?w=302&amp;h=232 302w\" alt=\"Sk\u00e6rmbillede 2014-07-10 kl. 00.08.05\" width=\"151\" height=\"116\" data-attachment-id=\"3880\" data-permalink=\"https:\/\/physioblogandreasbjerregaard.com\/2013\/06\/23\/laendesmerter-antibiotika-modic-forandringer-fysioterapi-nobelpris-modtagelse\/skaermbillede-2014-07-10-kl-00-08-05\/\" data-orig-file=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-08-05.png\" data-orig-size=\"1044,804\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;}\" data-image-title=\"Sk\u00e6rmbillede 2014-07-10 kl. 00.08.05\" data-image-description=\"\" data-medium-file=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-08-05.png?w=300\" data-large-file=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-08-05.png?w=825\" \/><\/a>Type 3 er forandringer karakteriseret ved fortykkelse af endeplader,\u00a0hvor den syge del af knoglen er omdannet til knoglearv\u00e6v.Nyere konsensus deler dog ikke modicforandringerne op.<\/li>\n<\/ul>\n<p><strong>Studierne<\/strong><\/p>\n<p>Hanne Albert f\u00f8rste pilot\u00a0<a href=\"http:\/\/bjsm.bmj.com\/content\/42\/12\/969.full\">projekt vidste ved (n)32 rygpatienter som modtag antibiotika i 90<\/a><a href=\"http:\/\/bjsm.bmj.com\/content\/42\/12\/969.full\"> dage<\/a>, at 60% af patienter blev raske eller fik det markant bedre m\u00e5lt p\u00e5\u00a0<a href=\"http:\/\/fysio.dk\/fafo\/Maleredskaber\/Maleredskaber-alfabetisk\/Roland-Morris-Questionnaire-\/\">Roland Morris\u00a0Questionnaire<\/a>\u00a0(MRQ)\u00a0som\u00a0belyser funktionsniveau hos patienter med Low Back Pain, dvs. skalaen m\u00e5ler nedsat funktion som f\u00f8lge af rygproblemer. (Se udregningerne p\u00e5 linket\u00a0<a href=\"http:\/\/bjsm.bmj.com\/content\/42\/12\/969.full\">her)<\/a><\/p>\n<p>Fors\u00f8get viste, at der efter 1 \u00e5rs follow-up, efter antibiotikabehandling p\u00e5 tre m\u00e5neder, var reducerede smerter hos 80% af patienterne med kronisk rygsmerter. Derudover var fors\u00f8gspersonernes ADL (activity of daily living) markant forbedret. Placebogruppen til denne unders\u00f8gelse vidste dog ingen effekt.<\/p>\n<p>N\u00e6ste projekt deltog (N)167 kronisk l\u00e6nderygsmerte patienter. De blev inddelt i to dobbeltblinded ramdomiserede grupper hvor af den ene gruppe blev behandlet med Bioclavid (amoxycillin-clavulanat 500mg\/125mg) tabletter tre gange om dagen, mens den anden gruppe fik placebo kalktabletter. For at deltage i projekt skulle deltagerne have haft\u00a0kronisk l\u00e6nderygsmerter med mere end 6 m\u00e5neders varighed og hos dem alle var smerterne\u00a0opst\u00e5et efter en tidligere discusprolaps. Hos deltager blev der ved Modic scanningen set ryghvirvelforandringer som st\u00f8der op til discusprolapsen, men det blev ikke udredt om der var en bakterial infektion tilstede (men kriterier gik ogs\u00e5 mest p\u00e5, om deltagerne havde haft ondt i mere end seks m\u00e5nder, frem for hvilken type modic forandringer de havde)<\/p>\n<p>Resultat viste, at tre ud af fire patienter havde f\u00e5et betydelig reducerede smerter og st\u00f8rre ADL funktion af antibiotikakuren.<\/p>\n<p>Unders\u00f8gelserne blev i april 2013 pr\u00e6senterede i European Spine Journal hvilket f\u00f8rte til hysterier blandt alverdens store aviser.<\/p>\n<blockquote><p><a href=\"http:\/\/www.guardian.co.uk\/society\/2013\/may\/07\/antibiotics-cure-back-pain-patients\">The Guardian<\/a>\u00a0af 7. maj 2013 \u201cUp to 40% of patients with chronic back pain could be cured with a course of antibiotics rather than surgery, in a medical breakthrough that one spinal surgeon says is worthy of a Nobel prize. In Britain today, around 4 million people can expect to suffer from chronic lower back pain at some point in their lives. The latest work suggests that more than half a million of them would benefit from antibiotics<\/p><\/blockquote>\n<p><strong>Hvordan vores ryghvivler smittes med en bakterie?<\/strong><\/p>\n<p><a href=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2013-06-23-kl-11-50-43.png\"><img decoding=\"async\" class=\"alignright\" src=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2013-06-23-kl-11-50-43.png?w=208&amp;h=210\" alt=\"Sk\u00e6rmbillede 2013-06-23 kl. 11.50.43\" width=\"208\" height=\"210\" \/><\/a>Den m\u00e5de jeg har forst\u00e5et den fremlagte litteratur p\u00e5, s\u00e5 opst\u00e5r Propion Acne bakterien i ryghvivlerne.<\/p>\n<p>Propion Acne\u00a0er dog en almindelig forekommende bakterie i b\u00e5de h\u00e5rs\u00e6kkene-, i huden- og i mundhulen. Ved eks. tandb\u00f8rstning kan de s\u00e5 komme i ber\u00f8ring med vores kredsl\u00f8bet. Dette udg\u00f8r umiddelbar ikke nogen risiko pga. vores indre \u201cblodmilj\u00f8\u201d godt kan nedbryde udfrakommende bakterier.<\/p>\n<p>Men n\u00e5r vi f\u00e5 en intervertebral diskus prolaps og n\u00e5r diskusmateraialet (necleus pulposus som bryder ud gennem anulus fribrosus, vil der inden for en kort tid opst\u00e5 en inflammation som bringer immunforsvaret \u00e6deceller (makrofager) til omr\u00e5det, som s\u00e5 <img loading=\"lazy\" decoding=\"async\" class=\"alignleft\" src=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2013-06-23-kl-11-50-52.png?w=300&amp;h=152\" alt=\"Sk\u00e6rmbillede 2013-06-23 kl. 11.50.52\" width=\"300\" height=\"152\" \/>skal bek\u00e6mpe denne\u00a0inflammation.<\/p>\n<p>Bakterien Propion Acne er kendt for at v\u00e6re en sekund\u00e6r lidelse til en inflammation. S\u00e5 n\u00e5r der ryddes op efter diskusinflammationen gennem vores et immunforsvarsystem, s\u00e5 vil P. Acne g\u00e5 i udbryd.<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-3881 \" src=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-06-27.png?w=215&amp;h=144\" sizes=\"(max-width: 215px) 100vw, 215px\" srcset=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-06-27.png?w=215&amp;h=144 215w, https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-06-27.png?w=430&amp;h=288 430w, https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-06-27.png?w=150&amp;h=100 150w, https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-06-27.png?w=300&amp;h=201 300w\" alt=\"Sk\u00e6rmbillede 2014-07-10 kl. 00.06.27\" width=\"215\" height=\"144\" data-attachment-id=\"3881\" data-permalink=\"https:\/\/physioblogandreasbjerregaard.com\/2013\/06\/23\/laendesmerter-antibiotika-modic-forandringer-fysioterapi-nobelpris-modtagelse\/skaermbillede-2014-07-10-kl-00-06-27\/\" data-orig-file=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-06-27.png\" data-orig-size=\"1162,778\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;}\" data-image-title=\"Sk\u00e6rmbillede 2014-07-10 kl. 00.06.27\" data-image-description=\"\" data-medium-file=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-06-27.png?w=300\" data-large-file=\"https:\/\/andreasbjerregaard.files.wordpress.com\/2013\/06\/skc3a6rmbillede-2014-07-10-kl-00-06-27.png?w=825\" \/>.<\/p>\n<p>.<\/p>\n<p><strong>Referencer:<\/strong><\/p>\n<p><a href=\"http:\/\/bjsm.bmj.com\/content\/42\/12\/969.full\">Antibiotic treatment in patients with low-back pain associated with Modic changes Type 1 (bone oedema): a pilot study<\/a><\/p>\n<p><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=Does+nuclear+tissue+infected+with+bacteria+following+disc+herniations+lead+to+Modic+changes+in+the+adjacent+vertebrae%3F\">Does\u00a0nuclear\u00a0tissue\u00a0infected\u00a0with\u00a0bacteria\u00a0following\u00a0disc\u00a0herniations\u00a0lead\u00a0to\u00a0Modic\u00a0changes\u00a0in the\u00a0adjacentvertebrae?<\/a><\/p>\n<h3><a href=\"http:\/\/updates.pain-topics.org\/2013\/05\/can-antibiotics-cure-chronic-back-pain.html\">Can Antibiotics Cure Chronic Back Pain?<\/a><\/h3>\n<p>Fysioterapeuten, juni 2013<\/p>\n<p><a href=\"http:\/\/bricksite.com\/modicklinikken\/hvad-er-modic-forandringer\">Modic forandringer<\/a><\/p>\n<p><a href=\"http:\/\/www.guardian.co.uk\/society\/2013\/may\/07\/antibiotics-cure-back-pain-patients\">The guardian: Antibiotics could cure 40% of chronic back pain patients<\/a><\/p>\n<div id=\"jp-post-flair\" class=\"sharedaddy sd-like-enabled sd-sharing-enabled\">\n<div class=\"sharedaddy sd-sharing-enabled\"><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Andreasbjerregaard.wordpress.com S\u00f8ernesfysioterapi L\u00e6nderyg problemer kan behandles med antibiotika Ny forskning viser at en antibiotikakur kan reducere kroniske rygsmerter efter en diskusprolaps. Bag forskningsresultaterne er et hold af fysioterapeuter og eksperter fra Syddansk Universitet\u00a0med Hanne Albert i spidsen, som gennem de seneste +10 \u00e5r har studerede antibiotika til behandling af l\u00e6nderygsmerter. Forskningen har v\u00e6ret finansieres af seks danske fonde og Gigtforeningen. Forskernes hypotese var, at nogle af rygsmerterne kunne skyldtes bakterier efter en injektion eller efter fx tandb\u00f8rstning. Fors\u00f8gene viste, at en betydelig procentdel af patienter med kronisk \u2018lavere\u2019 estimerede rygsmerter kan blive hjulpet eller have gavn af en 100-dages kur med antibiotikabehandling. Hvad Deres forskningen byggede p\u00e5\u00a0hvordan bakterielle infektioner i diskusmaterialet, ved en diskusprolaps, kunne forudsage smertefulde bet\u00e6ndelse tilstande og sm\u00e5 frakturer i den omgivende ryghvirvler [Albert, Lambert et al. 2013].\u00a0Disse forandringer blev\u00a0klassificererede efter Modic systemet, der i slutningen af 1980\u2019erne blev udviklet af Michael Modic til at beskrive forandringer i de lumbale l\u00e6ndehvirvlerne gennem MR-scanninger. P\u00e5 MR-scanninger kan der ved kronisk smertepatienter observeres nogle hvide pletter som sidder overfor- og nedenunder den tidl. prolaps. Det er disse hvide pletter som havde interesseret forskerholdet. Modic forandringer er en betegnelse for mikrobrud i rygs\u00f8jlen, som skaber en slags knogle\u00f8dem, som kan v\u00e6re yderst smertefulde for patienten. Dette heler sig selv i l\u00f8bet af 10-12 \u00e5r. (fysioterapeuten, 06 \/juni 2013).\u00a0Modic-forandringer \u00a0synes derfor at v\u00e6re forbundet med l\u00e6ndesmerter og kunne udg\u00f8re en pre-anatomisk \u00e5rsag til smerten. \u00a0\u00a0Klassiferingsfaser kaldes: Type 1, hvilket afspejler hypervaskularitet i hvirvlerne, sandsynligvis som et resultat af inflammation og \u00f8dem. Type 2 best\u00e5r af et gult fedtholdige udskiftninger af r\u00f8de knoglemarv i ryghvirvler. Type 3 er forandringer karakteriseret ved fortykkelse af endeplader,\u00a0hvor den syge del af knoglen er omdannet til knoglearv\u00e6v.Nyere konsensus deler dog ikke modicforandringerne op. Studierne Hanne Albert f\u00f8rste pilot\u00a0projekt vidste ved (n)32 rygpatienter som modtag antibiotika i 90 dage, at 60% af patienter blev raske eller fik det markant bedre m\u00e5lt p\u00e5\u00a0Roland Morris\u00a0Questionnaire\u00a0(MRQ)\u00a0som\u00a0belyser funktionsniveau hos patienter med Low Back Pain, dvs. skalaen m\u00e5ler nedsat funktion som f\u00f8lge af rygproblemer. (Se udregningerne p\u00e5 linket\u00a0her) Fors\u00f8get viste, at der efter 1 \u00e5rs follow-up, efter antibiotikabehandling p\u00e5 tre m\u00e5neder, var reducerede smerter hos 80% af patienterne med kronisk rygsmerter. Derudover var fors\u00f8gspersonernes ADL (activity of daily living) markant forbedret. Placebogruppen til denne unders\u00f8gelse vidste dog ingen effekt. N\u00e6ste projekt deltog (N)167 kronisk l\u00e6nderygsmerte patienter. De blev inddelt i to dobbeltblinded ramdomiserede grupper hvor af den ene gruppe blev behandlet med Bioclavid (amoxycillin-clavulanat 500mg\/125mg) tabletter tre gange om dagen, mens den anden gruppe fik placebo kalktabletter. For at deltage i projekt skulle deltagerne have haft\u00a0kronisk l\u00e6nderygsmerter med mere end 6 m\u00e5neders varighed og hos dem alle var smerterne\u00a0opst\u00e5et efter en tidligere discusprolaps. Hos deltager blev der ved Modic scanningen set ryghvirvelforandringer som st\u00f8der op til discusprolapsen, men det blev ikke udredt om der var en bakterial infektion tilstede (men kriterier gik ogs\u00e5 mest p\u00e5, om deltagerne havde haft ondt i mere end seks m\u00e5nder, frem for hvilken type modic forandringer de havde) Resultat viste, at tre ud af fire patienter havde f\u00e5et betydelig reducerede smerter og st\u00f8rre ADL funktion af antibiotikakuren. Unders\u00f8gelserne blev i april 2013 pr\u00e6senterede i European Spine Journal hvilket f\u00f8rte til hysterier blandt alverdens store aviser. The Guardian\u00a0af 7. maj 2013 \u201cUp to 40% of patients with chronic back pain could be cured with a course of antibiotics rather than surgery, in a medical breakthrough that one spinal surgeon says is worthy of a Nobel prize. In Britain today, around 4 million people can expect to suffer from chronic lower back pain at some point in their lives. The latest work suggests that more than half a million of them would benefit from antibiotics Hvordan vores ryghvivler smittes med en bakterie? Den m\u00e5de jeg har forst\u00e5et den fremlagte litteratur p\u00e5, s\u00e5 opst\u00e5r Propion Acne bakterien i ryghvivlerne. Propion Acne\u00a0er dog en almindelig forekommende bakterie i b\u00e5de h\u00e5rs\u00e6kkene-, i huden- og i mundhulen. Ved eks. tandb\u00f8rstning kan de s\u00e5 komme i ber\u00f8ring med vores kredsl\u00f8bet. Dette udg\u00f8r umiddelbar ikke nogen risiko pga. vores indre \u201cblodmilj\u00f8\u201d godt kan nedbryde udfrakommende bakterier. Men n\u00e5r vi f\u00e5 en intervertebral diskus prolaps og n\u00e5r diskusmateraialet (necleus pulposus som bryder ud gennem anulus fribrosus, vil der inden for en kort tid opst\u00e5 en inflammation som bringer immunforsvaret \u00e6deceller (makrofager) til omr\u00e5det, som s\u00e5 skal bek\u00e6mpe denne\u00a0inflammation. Bakterien Propion Acne er kendt for at v\u00e6re en sekund\u00e6r lidelse til en inflammation. S\u00e5 n\u00e5r der ryddes op efter diskusinflammationen gennem vores et immunforsvarsystem, s\u00e5 vil P. Acne g\u00e5 i udbryd. &nbsp; . . Referencer: Antibiotic treatment in patients with low-back pain associated with Modic changes Type 1 (bone oedema): a pilot study Does\u00a0nuclear\u00a0tissue\u00a0infected\u00a0with\u00a0bacteria\u00a0following\u00a0disc\u00a0herniations\u00a0lead\u00a0to\u00a0Modic\u00a0changes\u00a0in the\u00a0adjacentvertebrae? Can Antibiotics Cure Chronic Back Pain? Fysioterapeuten, juni 2013 Modic forandringer The guardian: Antibiotics could cure 40% of chronic back pain patients<\/p>\n","protected":false},"author":1,"featured_media":1125,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"postBodyCss":"","postBodyMargin":[],"postBodyPadding":[],"postBodyBackground":{"backgroundType":"classic","gradient":""},"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_wpcom_ai_launchpad_first_post":false,"_jetpack_hide_featured_image":false,"_jetpack_featured_image_duplicate_dismissed":0,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[168,172],"tags":[194,43],"class_list":["post-1123","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medicine","category-spine","tag-lowbackpain","tag-spine"],"blocksy_meta":{"styles_descriptor":{"styles":{"desktop":"","tablet":"","mobile":""},"google_fonts":[],"version":7}},"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 5.0.5 - aioseo.com -->\n\t<meta name=\"description\" content=\"Andreasbjerregaard.wordpress.com S\u00f8ernesfysioterapi L\u00e6nderyg problemer kan behandles med antibiotika Ny forskning viser at en antibiotikakur kan reducere kroniske rygsmerter efter en diskusprolaps. 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